A Daily Network publication
Explore the network
ETF Daily
The Definitive Daily Read on Exchange-Traded Funds
Sunday, August 23, 2026The Morning Brief →Sign in

Global X Genomics & Biotechnology ETF

$66.77+2.88% today
9.176752-WK

The fund invests at least 80% of its total assets in the securities of the underlying index. The underlying index is designed to provide exposure to exchange-listed companies that are positioned to benefit from further advances in the field of genomic science and biotechnology, as well as applications thereof (collectively, "Genomics & Biotechnology Companies"), as defined by Solactive AG, the provider of the underlying index. The fund is non-diversified.

Price & daily flows
61.354.146.966.77DAILY NET FLOWFeb 19Apr 21Jun 22Aug 21

SOURCE: MARKET TAPE & DAILY CREATION/REDEMPTION RECORDS · 6M SHOWN

The desk’s read

Flows are quiet — the past month netted out near zero, while the price has returned +46.2% so far this year. At 0.50% a year it is not the cheapest way in — IBRN runs the same ground at 0.47%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$85Massets under management
0.50%expense ratio · $50 per $10,000 a year
net flow, trailing month
20Kavg daily volume, 30 days
41holdings · US-domiciled
2019listed April 4, 2019 · beta -0.33
The book at a glance
MRNA+8.9%TWST+6.8%TXG+2.0%GH+1.7%ILMN+2.9%NTRA+2.2%VRTX+1.4%TECH+0.1%BMRN-1.4%ARWR-0.4%PRAX+3.1%QGEN-1.8%BNTX+5.1%CRSP+2.4%VCYT+1.2%LEGN+2.6%CAI+6.9%BEAM+4.8%QURE-1.1%LLY+0.9%RARE+2.0%WGS+5.5%CDNA+3.4%GILD+1.9%BLLN-0.3%SRPT-2.2%AZN+0.9%STOK+2.8%DHR+1.4%BMYPSNLWVE

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS TODAY’S MOVE · TOP 40 POSITIONS

HoldingsDownload CSV
#HoldingWeightPriceDay52-wk
1MRNAMODERNA7.10%$145.13+8.9%
2TWSTTWIST BIOSCIENCE6.20%$145.59+6.8%
3TXG10X GENOMICS5.58%$65.12+2.0%
4GHGUARDANT HEALTH5.55%$170.69+1.7%
5ILMNILLUMINA4.84%$219.40+2.9%
6NTRANATERA4.63%$332.03+2.2%
7VRTXVERTEX PHARMACEUTICALS3.65%$548.05+1.4%
8TECHBIO-TECHNE3.65%$72.32+0.1%
9BMRNBIOMARIN PHARMACEUTICAL3.70%$66.70-1.4%
10ARWRARROWHEAD PHARMACEUTICALS3.50%$87.11-0.4%
11PRAXPRAXIS PRECISION MEDICINES3.20%$375.94+3.1%
12QGENQIAGEN NV3.33%$44.07-1.8%
13BNTXBIONTECH SE3.02%$116.57+5.1%
14CRSPCRISPR THERAPEUTICS AG3.05%$59.50+2.4%
15VCYTVERACYTE2.51%$42.31+1.2%

The full book, free with one sign-in.

Top 15 positions are open to everyone. Sign in once and every fund’s complete holdings — plus CSV export, watchlists, and flow alerts — unlock across the network.

Sign in to see all 41
Sector weights
Healthcare100%
Health Technology99.08%
Health Services0.75%
Miscellaneous0.15%
Other0.06%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Country weights
United States92.49%
Hong Kong3.81%
Germany3.28%
China3.13%
Switzerland3.08%
Japan0.59%
Netherlands0.55%
Italy0.11%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Performance
1 week+13.0%
1 month+23.7%
3 months+43.5%
6 months+41.3%
YTD+46.2%
1 year+614.4%
3 years

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week
1 month
3 months
YTD
1 year

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows
SepOctNovDecJanFebMarAprMayJunJulAug
DAILY CREATION/REDEMPTION RECORDS, TRAILING TWELVE MONTHS
The risk read
52%realized volatility, 30 days (annualized)
143%realized volatility, 1 year
-18.2%deepest fall from a peak, 1 year
at peakwhere it sits vs. that peak today

The top holding is 7.1% of the book; the top ten carry 49%. Spread across 50+ names, it behaves like roughly 28 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
1calls today
puts today
put/call ratio
42Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$178M$164M
LLY ELI LILLY$65M$59M
BMY BRISTOL MYERS SQUIBB$3M$3M
VRTX VERTEX PHARMACEUTICALS$1M$3M
BNTX BIONTECH SE$2M$2M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against GNOM

Due diligence cuts both ways. These funds sit on the same shelf and beat GNOM on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
ITOT iShares Core S&P Total U.S. Stock Market ETF0.03%$97.9B+$245M-47bp on fee · 1157× the assets · +$245M in over the monthHead-to-head
IUSG iShares Core S&P U.S. Growth ETF0.04%$33.8B+$668M-46bp on fee · 399× the assets · +$668M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.7B+$104M-46bp on fee · 386× the assets · +$104M in over the monthHead-to-head
IUSV iShares Core S&P U.S. Value ETF0.04%$28.1B+$103M-46bp on fee · 332× the assets · +$103M in over the monthHead-to-head
IVV iShares Core S&P 500 ETF0.03%$900.9B−$14.2B-47bp on fee · 10641× the assetsHead-to-head
Sign in to save this to The RecordA timestamped copy for the file — documentation, not advice.
InstrumentsHarvest substitutesTrade cost at $1MClient tearsheetStress this fund
Every weekday · 6:30 a.m. ET

The Morning Brief

The private wealth industry in four minutes, every weekday at 6:30 a.m. ET. Free.