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Wednesday, August 19, 2026The Morning Brief →Sign in
IDNAISharesINDEX

iShares Genomics Immunology and Healthcare ETF

$40.75+13.26% today
224152-WK

The fund generally will invest at least 80% of its assets in the component securities of the index and in investments that have economic characteristics that are substantially identical to the component securities of the index and may invest up to 20% of its assets in certain futures, options and swap contracts, cash and cash equivalents. The index is composed of developed and emerging market companies that could benefit from the long-term growth and innovation in genomics, immunology and bioengineering. It is non-diversified.

Price & daily flows
38.034.330.640.75DAILY NET FLOWFeb 17Apr 17Jun 17Aug 19

SOURCE: MARKET TAPE & DAILY CREATION/REDEMPTION RECORDS · 6M SHOWN · NET +$36M OVER THIS RANGE

The desk’s read

Money keeps arriving — +$7M of net buying over the past month, about 3.3% of the fund's asset base, while the price has returned +55.4% so far this year. At 0.47% a year it is not the cheapest way in — IWM runs the same ground at 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$218Massets under management
0.47%expense ratio · $47 per $10,000 a year
+$7Mnet flow, trailing month
42Kavg daily volume, 30 days
63holdings · US-domiciled
2019listed June 10, 2019 · beta 0.96
The book at a glance
GSK+1.7%TWST-6.9%RVMD+1.9%MRNA-2.7%REGN+0.6%INCY-0.0%VRTX+2.6%MRK-0.6%BNTX+0.4%EXEL+1.5%IDYA+2.3%ROP+1.1%IBRX-2.4%IOVA-1.2%ABCL-0.6%CAI-3.2%RCUS+0.2%NUVB+7.3%CRSP-2.1%VIR+0.3%NVAX-2.0%KURA+8.8%JANX+4.4%CRVS-0.9%PSNL+0.4%RIGL+2.6%SAN-2.4%GMAB+0.5%IPN3.4%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS TODAY’S MOVE · TOP 40 POSITIONS

HoldingsDownload CSV
#HoldingWeightPriceDay52-wk
1GSKGSK3.17%$51.15+1.7%
2TWSTTWIST BIOSCIENCE5.89%$116.11-6.9%
3RVMDREVOLUTION MEDICINES4.66%$216.22+1.9%
4MRNAMODERNA4.45%$62.96-2.7%
5REGNREGENERON PHARMACEUTICALS4.16%$810.32+0.6%
6INCYINCYTE3.95%$123.42-0.0%
7VRTXVERTEX PHARMACEUTICALS3.78%$528.64+2.6%
8MRKMERCK & CO3.69%$135.12-0.6%
9BNTXBIONTECH SE3.41%$92.87+0.4%
10EXELEXELIXIS3.25%$53.11+1.5%
11IDYAIDEAYA BIOSCIENCES3.13%$37.49+2.3%
12ROPROPER TECHNOLOGIES3.50%$394.25+1.1%
13IBRXIMMUNITYBIO3.07%$7.73-2.4%
14IOVAIOVANCE BIOTHERAPEUTICS2.83%$7.03-1.2%
15ABCLABCELLERA BIOLOGICS2.70%$11.14-0.6%

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Sector weights
Health Care99.75%
Cash and/or Derivatives0.25%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Country weights
United States62.85%
Germany7.76%
France7.18%
Japan5.47%
Denmark4.35%
Switzerland3.5%
United Kingdom3.24%
Canada2.7%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Performance
1 week+15.0%
1 month+24.2%
3 months+42.9%
6 months+40.2%
YTD+55.4%
1 year
3 years

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week
1 month+$7M
3 months+$23M
YTD+$36M
1 year+$36M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows
AugSepOctNovDecJanFebMarAprMayJulAug
DAILY CREATION/REDEMPTION RECORDS, TRAILING TWELVE MONTHS
The risk read
45%realized volatility, 30 days (annualized)
28%realized volatility, 1 year
-10.7%deepest fall from a peak, 1 year
at peakwhere it sits vs. that peak today

The top holding is 5.9% of the book; the top ten carry 43%. Spread across 53+ names, it behaves like roughly 31 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
calls today
1puts today
put/call ratio
28Kshares traded
Most-traded holdings, options premiumBullishBearish
MRK MERCK & CO$3M$4M
RVMD REVOLUTION MEDICINES$2M$4M
MRNA MODERNA$2M$2M
VRTX VERTEX PHARMACEUTICALS$1M$2M
REGN REGENERON PHARMACEUTICALS$1M$1M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against IDNA

Due diligence cuts both ways. These funds sit on the same shelf and beat IDNA on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
IJH iShares Core S&P Mid-Cap ETF0.05%$128.4B+$547M-42bp on fee · 588× the assets · +$547M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.7B+$104M-43bp on fee · 150× the assets · +$104M in over the monthHead-to-head
IGSB iShares 1-5 Year Investment Grade Corporate Bond ETF0.04%$23.4B+$520M-43bp on fee · 107× the assets · +$520M in over the monthHead-to-head
IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF0.04%$18.7B+$312M-43bp on fee · 86× the assets · +$312M in over the monthHead-to-head
IEFA iShares Core MSCI EAFE ETF0.07%$195.3B+$631M-40bp on fee · 895× the assets · +$631M in over the monthHead-to-head
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InstrumentsHarvest substitutesTrade cost at $1MClient tearsheetStress this fund
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